Scott Forbes stars as the real-life adventurer Jim Bowie, aided by his ever-present weapon the Bowie Knife. "The Adventures of Jim Bowie" follows the exploits of Bowie before he moved to Texas (then part of Mexico), mainly in Opelousas and New Orleans. Bowie encounters many historical figures of the era, such as President Andrew Jackson, Jefferson Davis, John James Audubon, Sam Houston, and Davy Crockett. Guest stars include William Schallert, Denver Pyle, Michael Landon, Chuck Connors, Walter Coy, and June Carter Cash,